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Yeast under physiological changes of stress adaptation and stress recovery

ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Anthony Wright

PROVIDER: E-GEOD-36601 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Distinct roles of the Gcn5 histone acetyltransferase revealed during transient stress-induced reprogramming of the genome.

Xue-Franzén Yongtao Y Henriksson Johan J Bürglin Thomas R TR Wright Anthony P H AP

BMC genomics 20130716

<h4>Background</h4>Gcn5 belongs to a family of histone acetyltransferases (HATs) that regulate protein function by acetylation. Gcn5 plays several different roles in gene transcription throughout the genome but their characterisation by classical mutation approaches is hampered by the high degree of apparent functional redundancy between HAT proteins.<h4>Results</h4>Here we utilise the reduced redundancy associated with the transiently high levels of genomic reprogramming during stress adaptatio ...[more]

PMID: 23865462

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