Yeast translation
Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Yoav Arava
PROVIDER: E-GEOD-3732 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Genome-wide analysis of mRNA translation profiles in Saccharomyces cerevisiae.
Arava Yoav Y Wang Yulei Y Storey John D JD Liu Chih Long CL Brown Patrick O PO Herschlag Daniel D
Proceedings of the National Academy of Sciences of the United States of America 20030326 7
We have analyzed the translational status of each mRNA in rapidly growing Saccharomyces cerevisiae. mRNAs were separated by velocity sedimentation on a sucrose gradient, and 14 fractions across the gradient were analyzed by quantitative microarray analysis, providing a profile of ribosome association with mRNAs for thousands of genes. For most genes, the majority of mRNA molecules were associated with ribosomes and presumably engaged in translation. This systematic approach enabled us to recogni ...[more]
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