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Expression data of rhabdoid tumor cell line A204 treated with HDAC-inhibitor SAHA

ABSTRACT: Rhabdoid tumors are a highly aggressive pediatric tumor entity affecting infants and very young children. These tumors do not respond to conventional type chemotherapy. In recent approaches epigenetic compounds has been effective to inhibit cell growth of these tumors. Using microarray analysis we detect mechanism which are responsible for cell death induced by histone deacetylase inhibitors. A204 rhaboid tumor cell lines were treated for 12h with the HDAC inhibitor SAHA

ORGANISM(S): Homo sapiens

SUBMITTER: Kornelius Kerl

PROVIDER: E-GEOD-37373 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Expression data of rhabdoid tumor cell line A204 treated with HDAC-inhibitor SAHA

Project description:Rhabdoid tumors are a highly aggressive pediatric tumor entity affecting infants and very young children. These tumors do not respond to conventional type chemotherapy. In recent approaches epigenetic compounds has been effective to inhibit cell growth of these tumors. Using microarray analysis we detect mechanism which are responsible for cell death induced by histone deacetylase inhibitors.

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