Ontology highlight
ABSTRACT:
ORGANISM(S): Ciona intestinalis
SUBMITTER: Bradley Davidson
PROVIDER: E-GEOD-38313 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Developmental biology 20120514 1
The complex, partially redundant gene regulatory architecture underlying vertebrate heart formation has been difficult to characterize. Here, we dissect the primary cardiac gene regulatory network in the invertebrate chordate, Ciona intestinalis. The Ciona heart progenitor lineage is first specified by Fibroblast Growth Factor/Map Kinase (FGF/MapK) activation of the transcription factor Ets1/2 (Ets). Through microarray analysis of sorted heart progenitor cells, we identified the complete set of ...[more]