Unknown,Transcriptomics,Genomics,Proteomics

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Genome wide analysis of genes expressed in late G1/S phase of the cell cycle in PMCA4 wild type (P4WT), PMCA4 knockout(P4KO), P4KO rescued with PMCA4b and P4KO rescued with Vector primary vascular smooth muscle cells


ABSTRACT: Husain lab cell proliferation in vitro experimental data showed that electroporating PMCA4b cDNA into P4KO cells rescued the G1 arrest phenotype in P4KO primary vascular smooth muscle cells (VSMC). This microarray documents the different gene expression profiles of P4WT, P4KO, P4KO+PMCA4b and P4KO+Vector VSMC at the late G1/S stage in serum synchronized cell populations (n=4 or 5 populations for each genotype). Serum synchronized late G1/S stage cell populations (P4WT, P4KO, P4KO+PMCA4b and P4KO+Vector) were employed to extract total RNA which was used for microarray analysis.

ORGANISM(S): Mus musculus

SUBMITTER: Mansoor Husain 

PROVIDER: E-GEOD-38319 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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