Growth phase-dependent response of Helicobacter pylori to iron starvation.
Ontology highlight
ABSTRACT:
ORGANISM(S): Helicobacter pylori
SUBMITTER: Douglas Merrell
PROVIDER: E-GEOD-3888 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Growth phase-dependent response of Helicobacter pylori to iron starvation.
Merrell D Scott DS Thompson Lucinda J LJ Kim Charles C CC Mitchell Hazel H Tompkins Lucy S LS Lee Adrian A Falkow Stanley S
Infection and immunity 20031101 11
Iron is an essential nutrient that is often found in extremely limited available quantities within eukaryotic hosts. Because of this, many pathogenic bacteria have developed regulated networks of genes important for iron uptake and storage. In addition, it has been shown that many bacteria use available iron concentrations as a signal to regulate virulence gene expression. We have utilized DNA microarray technology to identify genes of the human pathogen Helicobacter pylori that are differential ...[more]
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