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Canine lymphoma tissues

ABSTRACT: Tumor tissues from canine lymphomas with accompanying survival and breed data. Gene expression analysis of samples representing common histologic subtypes of canine lymphoma.

ORGANISM(S): Canis lupus familiaris

SUBMITTER: Aaron Sarver

PROVIDER: E-GEOD-39365 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Molecular profiling reveals prognostically significant subtypes of canine lymphoma.

Frantz A M AM Sarver A L AL Ito D D Phang T L TL Karimpour-Fard A A Scott M C MC Valli V E O VE Lindblad-Toh K K Burgess K E KE Husbands B D BD Henson M S MS Borgatti A A Kisseberth W C WC Hunter L E LE Breen M M O'Brien T D TD Modiano J F JF

Veterinary pathology 20121102 4

We performed genomewide gene expression analysis of 35 samples representing 6 common histologic subtypes of canine lymphoma and bioinformatics analyses to define their molecular characteristics. Three major groups were defined on the basis of gene expression profiles: (1) low-grade T-cell lymphoma, composed entirely by T-zone lymphoma; (2) high-grade T-cell lymphoma, consisting of lymphoblastic T-cell lymphoma and peripheral T-cell lymphoma not otherwise specified; and (3) B-cell lymphoma, consi ...[more]

PMID: 23125145

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