Ontology highlight
ABSTRACT:
ORGANISM(S): Candida albicans SC5314
SUBMITTER: Anna Buschart
PROVIDER: E-GEOD-39715 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Journal of medical microbiology 20120823 Pt 12
The fungicide fludioxonil is widely used in agriculture. Residua of this fungicide are occasionally detected in fruits and can therefore be ingested by humans. The human fungal pathogen Candida albicans expresses the target of fludioxonil, Nik1p, a type III histidine kinase involved in stress response. Inhibition of yeast and hyphae growth was hardly observable after treatment of C. albicans SC5314 with fludioxonil. As a side effect, however, we observed a concentration-dependent induction of th ...[more]