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Human monocyte-derived DCs: effect of IL-4 superkines

ABSTRACT: Gene expression induced by IL-4 and IL-4 superkines on CD14+ monocytes cultured in the presence of GM-CSF. Super-4 and KFR signal preferentially through the type I and type II IL-4 receptor, respectively. Five biological replicates (n=5 healthy donors), four conditions: GM-CSF alone or in combination with IL-4, Super-4 or KFR. Two colors: Cy3 for GM-CSF alone, Cy5 for any combination. Cells were cultured for 6 hours with 50 ng/ml of GM-CSF and 20 ng/ml of IL-4, Super-4 or KFR.

ORGANISM(S): Homo sapiens

SUBMITTER: Remi Creusot

PROVIDER: E-GEOD-40200 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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