Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Constitutional Trisomy 8 Mosaicism as a Model for Epigenetic Studies of Aneuploidy (microRNA)


ABSTRACT: To increase our understanding of epigenetic patterns associated with aneuploidy we used constitutional trisomy 8 mosaicism as a model, enabling analyses of single cell clones, harboring either trisomy or disomy 8, from the same patient. We profiled gene and miRNA expression as well as genome-wide and promoter specific DNA methylation and hydroxymethylation patterns in trisomic and disomic fibroblasts, using microarrays and methylated DNA immunoprecipitation. comparison of trisomy 8 cells with disomic as well as reference fibroblasts

ORGANISM(S): Homo sapiens

SUBMITTER: Josef Davidsson 

PROVIDER: E-GEOD-40319 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

Similar Datasets

2012-12-01 | E-GEOD-40320 | biostudies-arrayexpress
2012-12-01 | E-GEOD-40317 | biostudies-arrayexpress
2012-12-01 | GSE40319 | GEO
2012-12-01 | GSE40317 | GEO
2012-12-01 | GSE40320 | GEO
| S-EPMC3704342 | biostudies-literature
2012-10-23 | E-GEOD-38931 | biostudies-arrayexpress
2012-12-01 | GSE40321 | GEO
2018-05-30 | GSE110064 | GEO
2023-01-07 | GSE222365 | GEO