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Differential gene expression analysis of U87MG EGFRvA cells vs. U87MG EGFR cells

ABSTRACT: EGFRvA is a novel and widely-expressed EGFR isoform, whose upregulation is positively related to glioma grades. Intriguingly, it is the upregulation of EGFRvA but not EGFR that significantly correlates with a poor prognosis in glioma patients. Cancer cells expressing EGFRvA (relative to EGFR) display a higher invasive capacity and a lower sensitivity to EGFR tyrosine kinase inhibitors (TKIs). To investigate the significant differently expressed genes between U87MG EGFRvA cells and U87MG EGFR cellsM-oM-

ORGANISM(S): Homo sapiens

SUBMITTER: Min Zhou

PROVIDER: E-GEOD-41230 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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