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Differential gene expression analysis of U87MG EGFRvA cells vs. U87MG EGFR cells

ABSTRACT: EGFRvA is a novel and widely-expressed EGFR isoform, whose upregulation is positively related to glioma grades. Intriguingly, it is the upregulation of EGFRvA but not EGFR that significantly correlates with a poor prognosis in glioma patients. Cancer cells expressing EGFRvA (relative to EGFR) display a higher invasive capacity and a lower sensitivity to EGFR tyrosine kinase inhibitors (TKIs). To investigate the significant differently expressed genes between U87MG EGFRvA cells and U87MG EGFR cells，microarray experiments were conducted.

ORGANISM(S): Homo sapiens

PROVIDER: GSE41230 | GEO | 2012/09/30

SECONDARY ACCESSION(S): PRJNA176270

REPOSITORIES: GEO

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Differential gene expression analysis of U87MG EGFRvA cells vs. U87MG EGFR cells

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