Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Transcriptome-wide miR-155 binding map reveals widespread non-canonical microRNA targeting


ABSTRACT: This SuperSeries is composed of the following subset Series: GSE41241: Transcriptome-wide miR-155 binding map reveals widespread non-canonical microRNA targeting [mRNA expression data] GSE41285: Transcriptome-wide miR-155 binding map reveals widespread non-canonical microRNA targeting [CLIP-seq data] Refer to individual Series

ORGANISM(S): Mus musculus

SUBMITTER: Aly Khan 

PROVIDER: E-GEOD-41288 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

altmetric image

Publications

Transcriptome-wide miR-155 binding map reveals widespread noncanonical microRNA targeting.

Loeb Gabriel B GB   Khan Aly A AA   Canner David D   Hiatt Joseph B JB   Shendure Jay J   Darnell Robert B RB   Leslie Christina S CS   Rudensky Alexander Y AY  

Molecular cell 20121108 5


MicroRNAs (miRNAs) are essential components of gene regulation, but identification of miRNA targets remains a major challenge. Most target prediction and discovery relies on perfect complementarity of the miRNA seed to the 3' untranslated region (UTR). However, it is unclear to what extent miRNAs target sites without seed matches. Here, we performed a transcriptome-wide identification of the endogenous targets of a single miRNA-miR-155-in a genetically controlled manner. We found that approximat  ...[more]

Similar Datasets

2012-11-09 | E-GEOD-41285 | biostudies-arrayexpress
2016-01-20 | E-GEOD-76967 | biostudies-arrayexpress
2011-05-24 | E-GEOD-29460 | biostudies-arrayexpress
2015-06-16 | E-GEOD-67990 | biostudies-arrayexpress
2008-04-05 | E-GEOD-10036 | biostudies-arrayexpress
2011-04-19 | E-GEOD-28591 | biostudies-arrayexpress
2016-06-15 | E-GEOD-79929 | biostudies-arrayexpress
2012-10-05 | E-GEOD-41357 | biostudies-arrayexpress
2013-03-15 | E-GEOD-45148 | biostudies-arrayexpress
2010-11-04 | E-GEOD-25032 | biostudies-arrayexpress