Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Shihori Tanabe
PROVIDER: E-GEOD-42252 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Tanabe Shihori S Aoyagi Kazuhiko K Yokozaki Hiroshi H Sasaki Hiroki H
International journal of oncology 20140411 6
Epithelial-mesenchymal transition (EMT) is associated with tumor malignancy. The hedgehog-EMT pathway is preferentially activated in diffuse-type gastric cancer (GC) compared with intestinal-type GC; however, histological typing is currently the only method for distinguishing these two major types of GC. We compared the gene expression profiles of 12 bone marrow-derived mesenchymal stem cell cultures and 5 diffuse-type GC tissue samples. Numerous upregulated or downregulated genes were identifie ...[more]