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Transcription profiling of human, bonobo and gorilla fibroblast cell cultures

ABSTRACT: Data files from Genome Research paper 'Comparative analysis of gene expression patterns in human and African great ape cultured fibroblasts'

ORGANISM(S): Homo sapiens

SUBMITTER: Shailender Nagpal

PROVIDER: E-GEOD-426 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Comparative analysis of gene-expression patterns in human and African great ape cultured fibroblasts.

Karaman Mazen W MW Houck Marlys L ML Chemnick Leona G LG Nagpal Shailender S Chawannakul Daniel D Sudano Dominick D Pike Brian L BL Ho Vincent V VV Ryder Oliver A OA Hacia Joseph G JG

Genome research 20030701 7

Although much is known about genetic variation in human and African great ape (chimpanzee, bonobo, and gorilla) genomes, substantially less is known about variation in gene-expression profiles within and among these species. This information is necessary for defining transcriptional regulatory networks that contribute to complex phenotypes unique to humans or the African great apes. We took a systematic approach to this problem by investigating gene-expression profiles in well-defined cell popul ...[more]

PMID: 12840040

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