Ontology highlight
ABSTRACT:
ORGANISM(S): [Clostridium] difficile
SUBMITTER: Monot Marc
PROVIDER: E-GEOD-43202 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Saujet Laure L Pereira Fátima C FC Serrano Monica M Soutourina Olga O Monot Marc M Shelyakin Pavel V PV Gelfand Mikhail S MS Dupuy Bruno B Henriques Adriano O AO Martin-Verstraete Isabelle I
PLoS genetics 20131003 10
Clostridium difficile, a Gram positive, anaerobic, spore-forming bacterium is an emergent pathogen and the most common cause of nosocomial diarrhea. Although transmission of C. difficile is mediated by contamination of the gut by spores, the regulatory cascade controlling spore formation remains poorly characterized. During Bacillus subtilis sporulation, a cascade of four sigma factors, σ(F) and σ(G) in the forespore and σ(E) and σ(K) in the mother cell governs compartment-specific gene expressi ...[more]