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Metabolic syndrome exercise training

ABSTRACT: We assessed vastus lateralis muscle gene expression levels of 12 women with the metabolic syndrome before and after a 6 month exercise training program RNA was isolated from a vastus lateralis muscle biopsy of 6 women with the metabolic syndrome before and after a 6 month guided endurance exercise training program

ORGANISM(S): Homo sapiens

SUBMITTER: Gerwen Lammers

PROVIDER: E-GEOD-43760 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Upregulation of skeletal muscle inflammatory genes links inflammation with insulin resistance in women with the metabolic syndrome.

Poelkens Fleur F Lammers Gerwen G Pardoel Elisabeth M EM Tack Cees J CJ Hopman Maria T E MT

Experimental physiology 20130614 10

The metabolic syndrome, a combination of interrelated metabolic risk factors, is associated with insulin resistance and promotes the development of cardiovascular diseases and type 2 diabetes mellitus. There is a close link between inflammation and metabolic disease, but the responsible mechanisms remain elusive. The aim of this study was to identify differentially expressed genes in insulin-resistant skeletal muscle tissue of women with the metabolic syndrome compared with healthy control women ...[more]

PMID: 23771909

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Metabolic syndrome exercise training

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