Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Andrea Vecchione
PROVIDER: E-GEOD-43867 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Vecchione Andrea A Belletti Barbara B Lovat Francesca F Volinia Stefano S Chiappetta Gennaro G Giglio Simona S Sonego Maura M Cirombella Roberto R Onesti Elisa Concetta EC Pellegrini Patrizia P Califano Daniela D Pignata Sandro S Losito Simona S Canzonieri Vincenzo V Sorio Roberto R Alder Hansjuerg H Wernicke Dorothee D Stoppacciaro Antonella A Baldassarre Gustavo G Croce Carlo M CM
Proceedings of the National Academy of Sciences of the United States of America 20130522 24
Epithelial ovarian cancer is the most lethal gynecologic malignancy; it is highly aggressive and causes almost 125,000 deaths yearly. Despite advances in detection and cytotoxic therapies, a low percentage of patients with advanced stage disease survive 5 y after the initial diagnosis. The high mortality of this disease is mainly caused by resistance to the available therapies. Here, we profiled microRNA (miR) expression in serous epithelial ovarian carcinomas to assess the possibility of a miR ...[more]