Unknown,Transcriptomics,Genomics,Proteomics

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Analysis of genes regulated by AS1 and AS2


ABSTRACT: AS1 and AS2 encode MYB related protein and AS2-domain containing protein, respectively and may regulate transcription. These genes are involved in the determination of axes of leaves of Arabidopsis thaliana. To know the gene regulation in the leaf development, expression profile among wild-type, as1 and as2 mutants and AS2 overexpression plants were compaired. shoot apices from as1-1, as2-1, AS2 overexpressing, and wild type embryos

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Hiro Takahashi 

PROVIDER: E-GEOD-44028 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Meta-analyses of microarrays of Arabidopsis asymmetric leaves1 (as1), as2 and their modifying mutants reveal a critical role for the ETT pathway in stabilization of adaxial-abaxial patterning and cell division during leaf development.

Takahashi Hiro H   Iwakawa Hidekazu H   Ishibashi Nanako N   Kojima Shoko S   Matsumura Yoko Y   Prananingrum Pratiwi P   Iwasaki Mayumi M   Takahashi Anna A   Ikezaki Masaya M   Luo Lilan L   Kobayashi Takeshi T   Machida Yasunori Y   Machida Chiyoko C  

Plant & cell physiology 20130208 3


It is necessary to use algorithms to analyze gene expression data from DNA microarrays, such as in clustering and machine learning. Previously, we developed the knowledge-based fuzzy adaptive resonance theory (KB-FuzzyART), a clustering algorithm suitable for analyzing gene expression data, to find clues for identifying gene networks. Leaf primordia form around the shoot apical meristem (SAM), which consists of indeterminate stem cells. Upon initiation of leaf development, adaxial-abaxial patter  ...[more]

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