Dataset Information
IER3-AS1 interacting proteins by AP-MS
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: 
Ekaterina Mirgorodskaya
LAB HEAD: Chandrasekhar Kanduri
PROVIDER: PXD035704 | Pride | 2022-10-15
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| 4114_PD_file_search_log.xlsx | Xlsx | |||
| 4114_SPh_T-1mc_Ox-MMTS_Decoy_Fusion_201127_5-10.pdResult | Other | |||
| Fusion_201127_05.msf | Msf | |||
| Fusion_201127_05.raw | Raw | |||
| Fusion_201127_06.msf | Msf |
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Publications
HnRNPK maintains single strand RNA through controlling double-strand RNA in mammalian cells.
Nature communications 20220829 1
Although antisense transcription is a widespread event in the mammalian genome, double-stranded RNA (dsRNA) formation between sense and antisense transcripts is very rare and mechanisms that control dsRNA remain unknown. By characterizing the FGF-2 regulated transcriptome in normal and cancer cells, we identified sense and antisense transcripts IER3 and IER3-AS1 that play a critical role in FGF-2 controlled oncogenic pathways. We show that IER3 and IER3-AS1 regulate each other's transcription th ...[more]
