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Flutamide treated rat hepatocytes in microfluidic biochips

ABSTRACT: We investigated the effects of the flutamide (FLU) -induced liver injury in primary rat hepatocytes using our liver microfluidic biochips. Flutamide is used a non-steroidal anti-androgenic drug. Two flutamide concentrations, 10M-BM-5M and 100M-BM-5M, were used to expose the hepatocytes for 24h under perfusion. Primary rat hepatocytes were cultivated in microfluidic biochips and treated with 10 and 100M-BM-5M of flutamide for 24h

ORGANISM(S): Rattus norvegicus

SUBMITTER: Florent Dumont

PROVIDER: E-GEOD-44317 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Flutamide treated rat hepatocytes in microfluidic biochips

Project description:We investigated the effects of the flutamide (FLU) -induced liver injury in primary rat hepatocytes using our liver microfluidic biochips. Flutamide is used a non-steroidal anti-androgenic drug. Two flutamide concentrations, 10µM and 100µM, were used to expose the hepatocytes for 24h under perfusion.

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