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Rhesus macaque model of hCoV-EMC respiratory infection

ABSTRACT: Microarray analysis of peripheral blood mononuclear cells (PBMCs), lungs, and lung lesions collected over the course of hCoV-EMC infection of 6 rhesus macaques. 6 rhesus macaques were infected intratracheally with hCoV-EMC. PBMCs were collected at days 0, 1, 3, and 6, and lungs were collected from serial sacrifices of 3 animals each at day 3 and day 6. Infection produced a mild-moderate, self-limiting respiratory infection, and was not lethal. We performed microarray analysis (using Agilent Rhesus arrays) on all lungs, lung lesions, and PBMCs collected for the study.

ORGANISM(S): Macaca mulatta

SUBMITTER: Michael Katze

PROVIDER: E-GEOD-44542 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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