Ontology highlight
ABSTRACT:
ORGANISM(S): Arabidopsis thaliana
SUBMITTER: Lan Yang
PROVIDER: E-GEOD-44635 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Huang Chao-Feng CF Miki Daisuke D Tang Kai K Zhou Hao-Ran HR Zheng Zhimin Z Chen Wei W Ma Ze-Yang ZY Yang Lan L Zhang Heng H Liu Renyi R He Xin-Jian XJ Zhu Jian-Kang JK
PLoS genetics 20130912 9
Cytosine DNA methylation is a stable epigenetic mark that is frequently associated with the silencing of genes and transposable elements (TEs). In Arabidopsis, the establishment of DNA methylation is through the RNA-directed DNA methylation (RdDM) pathway. Here, we report the identification and characterization of RDM16, a new factor in the RdDM pathway. Mutation of RDM16 reduced the DNA methylation levels and partially released the silencing of a reporter gene as well as some endogenous genomic ...[more]