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MiR-155 promotes blood-brain barrier dysfunction in neuroinflammation (part 1)

ABSTRACT: Here, we investigated the time-course changes in the pattern of microRNA (miRNA) expression of TNFα and IFNγ-stimulated and unstimulated hCMEC/D3 cells, an immortalized human cerebral microvascular endothelial cell line. In order to investigate pro-inflammatory cytokine-induced changes in miRNA levels in hCMEC/D3 cells, we challenged brain endothelial cells with TNFα and IFNγ (100 ng/ml) for 2 h, 6 h and 24 h and determined microRNA expression in cytokine-stimulated and unstimulated cells

ORGANISM(S): Homo sapiens

SUBMITTER: Miguel Lopez-Ramirez

PROVIDER: E-GEOD-44692 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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MiR-155 promotes blood-brain barrier dysfunction in neuroinflammation

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