Methanopyrus kandleri small RNA analysis
Ontology highlight
ABSTRACT:
ORGANISM(S): Methanopyrus kandleri AV19
SUBMITTER: Lennart Randau
PROVIDER: E-GEOD-44979 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
RNA-Seq analyses reveal the order of tRNA processing events and the maturation of C/D box and CRISPR RNAs in the hyperthermophile Methanopyrus kandleri.
Su Andreas A H AA Tripp Vanessa V Randau Lennart L
Nucleic acids research 20130425 12
The methanogenic archaeon Methanopyrus kandleri grows near the upper temperature limit for life. Genome analyses revealed strategies to adapt to these harsh conditions and elucidated a unique transfer RNA (tRNA) C-to-U editing mechanism at base 8 for 30 different tRNA species. Here, RNA-Seq deep sequencing methodology was combined with computational analyses to characterize the small RNome of this hyperthermophilic organism and to obtain insights into the RNA metabolism at extreme temperatures. ...[more]
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