Transcriptoma analysis of B splenocytes of 3'RR-deficient mice and wt mice
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ABSTRACT: The IgH 3' regulatory region (3'RR) controls class switch recombination and somatic hypermutation in mice. Similar numbers of B cells are found in spleen of 3'RR-deficient mice and wt mice. We compare their transcriptoma in order to find differences in their maturation status. B splenocytes from four wt mice and four 3'RR-deficient mice are investigated. Splenic B cells are purified with anti-B220-coupled beads.
ORGANISM(S): Mus musculus
SUBMITTER: Kevin Lebrigand
PROVIDER: E-GEOD-45230 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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