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NcRNA profiling after Influenza A/WSN/33 infection II

ABSTRACT: 8h and 24h after A/WSN/33 infection (MOI 1) ncRNA profiling was performed A growing body of evidence suggests gene regulatory functions for the majority of non-protein-coding RNAs (ncRNAs). Besides small RNAs (sRNAs), the diverse class of long ncRNAs (lncRNAs) recently came into focus of research. So far, the relevance of lncRNAs in infection processes remains elusive. Here, we report the differential expression of several classes of lncRNAs during influenza A virus (IAV) infection in human lung epithelial cells. 2 biological replicates of 8h and 24h infection were hybridzed in an independent color-swap

ORGANISM(S): Homo sapiens

SUBMITTER: Carla Winterling

PROVIDER: E-GEOD-45398 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Evidence for a crucial role of a host non-coding RNA in influenza A virus replication.

Winterling Carla C Koch Manuel M Koeppel Max M Garcia-Alcalde Fernando F Karlas Alexander A Meyer Thomas F TF

RNA biology 20131220 1

A growing body of evidence suggests the non-protein coding human genome is of vital importance for human cell function. Besides small RNAs, the diverse class of long non-coding RNAs (lncRNAs) recently came into focus. However, their relevance for infection, a major evolutionary driving force, remains elusive. Using two commercially available microarray systems, namely NCode™ and Sureprint™ G3, we identified differential expression of 42 ncRNAs during influenza A virus (IAV) infection in human lu ...[more]

PMID: 24440876

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2014-01-29 | E-GEOD-45397 | biostudies-arrayexpress

Evidence for a Crucial Role of a Host Non-coding RNA in Influenza A Virus Replication

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

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