Ontology highlight
ABSTRACT:
ORGANISM(S): Danio rerio
SUBMITTER: Amit Cohen
PROVIDER: E-GEOD-45562 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Zebrafish 20130615 5
Estrogen is a steroid hormone that has been implicated in a variety of cellular and physiological processes and in the development of diseases such as cancer. Here we show a remarkable widespread microRNA (miRNA) downregulation in the zebrafish (Danio rerio) liver following 17β-estradiol (E2) treatment. This unique miRNA expression signature in the fish liver was further supported by a combination of computational predictions with gene expression microarray data, showing a significant bias towar ...[more]