Unknown,Transcriptomics,Genomics,Proteomics

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Mouse spleen: wild type vs leukemic


ABSTRACT: mRNA profiling of mouse spleens comparing wild type spleens vs. spleens from mice having deletion of RBP-J in cells of the renin lineage which results in B-cell leukemia We used microarrays to detail the global program of gene expression in wild type and the leukemic spleens which revealed upregulation of genes for cell cycle progression and B cell identity in the leukemic spleens. Two condition experiment: wild type vs leukemic; biological replicates: individual mice - 2 wild type, 2 mutant. One replicate per array.

ORGANISM(S): Mus musculus

SUBMITTER: R. Ariel Gomez 

PROVIDER: E-GEOD-46229 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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