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Unknown,Transcriptomics,Genomics,Proteomics

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Small RNA-seq of human granulosa cells reveals miRNAs in FSHR and aromatase genes

ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Homo sapiens

SUBMITTER: Agne Velthut-Meikas

PROVIDER: E-GEOD-46508 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Research resource: small RNA-seq of human granulosa cells reveals miRNAs in FSHR and aromatase genes.

Velthut-Meikas Agne A Simm Jaak J Tuuri Timo T Tapanainen Juha S JS Metsis Madis M Salumets Andres A

Molecular endocrinology (Baltimore, Md.) 20130509 7

The granulosa cells in the mammalian ovarian follicle respond to gonadotropin signaling and are involved in the processes of folliculogenesis and oocyte maturation. Studies on gene expression and regulation in human granulosa cells are of interest due to their potential for estimating the oocyte viability and in vitro fertilization success. However, the posttranscriptional gene expression studies on micro-RNA (miRNA) level in the human ovary have been scarce. The current study determined the miR ...[more]

PMID: 23660593

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