Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Eric Hoffman
PROVIDER: E-GEOD-469 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Zhao Po P Iezzi Simona S Carver Ethan E Dressman Devin D Gridley Thomas T Sartorelli Vittorio V Hoffman Eric P EP
The Journal of biological chemistry 20020521 33
Temporal expression profiling was utilized to define transcriptional regulatory pathways in vivo in a mouse muscle regeneration model. Potential downstream targets of MyoD were identified by temporal expression, promoter data base mining, and gel shift assays; Slug and calpain 6 were identified as novel MyoD targets. Slug, a member of the snail/slug family of zinc finger transcriptional repressors critical for mesoderm/ectoderm development, was further shown to be a downstream target by using pr ...[more]