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Identification of a macrophage PPARÎ³-GDF3 regulatory axis controlling muscle regeneration

ABSTRACT: Muscle injury was elicited by cardiotoxin injection into the tibialis anterior muscle. Macrophages were isolated 2 days post-injury from the regenerating muscle. We used microarray to obtain global gene expression data of muscle-derived tissue macrophage subsets. Tissue macrophages were collected from regenerating muscle samples of three animals, Ly6C+ F4/80low and Ly6C- F4/80high macrophage subsets were sorted. The global gene expression patterns of distinct macrophage subsets were analyzed on Affymetrix microarrays.

ORGANISM(S): Mus musculus

SUBMITTER: Szilard Poliska

PROVIDER: E-GEOD-71155 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Tissue macrophage subsets derived from regenerating muscle

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Mus musculus

Project description:Tissue macrophage subsets derived from regenerating muscle

| PRJNA188463 | ENA

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