Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Benjamin Laufer
PROVIDER: E-GEOD-47111 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Laufer Benjamin I BI Mantha Katarzyna K Kleiber Morgan L ML Diehl Eric J EJ Addison Sean M F SM Singh Shiva M SM
Disease models & mechanisms 20130410 4
Fetal alcohol spectrum disorders (FASDs) are characterized by life-long changes in gene expression, neurodevelopment and behavior. What mechanisms initiate and maintain these changes are not known, but current research suggests a role for alcohol-induced epigenetic changes. In this study we assessed alterations to adult mouse brain tissue by assaying DNA cytosine methylation and small noncoding RNA (ncRNA) expression, specifically the microRNA (miRNA) and small nucleolar RNA (snoRNA) subtypes. W ...[more]