Secreted and membrane-associated genes
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: M Diehn
PROVIDER: E-GEOD-48 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Large-scale identification of secreted and membrane-associated gene products using DNA microarrays.
Diehn M M Eisen M B MB Botstein D D Brown P O PO
Nature genetics 20000501 1
Membrane-associated and secreted proteins are an important class of proteins and include receptors, transporters, adhesion molecules, hormones and cytokines. Although algorithms have been developed to recognize potential amino-terminal membrane-targeting signals or transmembrane domains in protein sequences, their accuracy is limited and they require knowledge of the entire coding sequence, including the N terminus, which is not currently available for most of the genes in most organisms, includ ...[more]
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