Unknown,Transcriptomics,Genomics,Proteomics

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Expression data from Th17 cells of different origins


ABSTRACT: Foxp3 is indispensable for Treg suppressive function, but the stability of Foxp3 has been controversial. In autoimmune arthritis, Th17 cells play a critically important pathological role, but the origin of Th17 cells remains unknown We used microarrays to detail the global programme of gene expression of Th17 cells originated from Foxp3+T cells compared to conventional naive CD4+T cells derived Th17 cells. We also take samples of Treg cells and Th0 cells for the experimetnatl control. Each T cell subset after the culture was subjected to RNA extraction and hybridization on Affymetrix microarrays.

ORGANISM(S): Mus musculus

SUBMITTER: Noriko Komatsu 

PROVIDER: E-GEOD-48428 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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