Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Ronald Hart
PROVIDER: E-GEOD-48818 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Edwards Shanique K E SK Baron Jacqueline J Moore Carissa R CR Liu Yan Y Perlman David H DH Hart Ronald P RP Xie Ping P
Journal of hematology & oncology 20140909
<h4>Background</h4>Identification of novel genetic risk factors is imperative for a better understanding of B lymphomagenesis and for the development of novel therapeutic strategies. TRAF3, a critical regulator of B cell survival, was recently recognized as a tumor suppressor gene in B lymphocytes. The present study aimed to identify novel oncogenes involved in malignant transformation of TRAF3-deficient B cells.<h4>Methods</h4>We used microarray analysis to identify genes differentially express ...[more]