Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

The prognostic and predictive value of a six-microRNA-based classifier in stage II colon cancer

ABSTRACT: microRNA profiling of colon tumor tissues vs adjacent normal tissues 40 paired tumor and adjacent normal tissues of stage M-bM-^EM-! colon caner

ORGANISM(S): Homo sapiens

SUBMITTER: Zhenhua Chen

PROVIDER: E-GEOD-49246 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Prognostic and predictive value of a microRNA signature in stage II colon cancer: a microRNA expression analysis.

Zhang Jia-Xing JX Song Wu W Chen Zhen-Hua ZH Wei Jin-Huan JH Liao Yi-Ji YJ Lei Jian J Hu Ming M Chen Geng-Zhen GZ Liao Bing B Lu Jian J Zhao Hong-Wei HW Chen Wei W He Yu-Long YL Wang Hui-Yun HY Xie Dan D Luo Jun-Hang JH

The Lancet. Oncology 20131113 13

<h4>Background</h4>Current staging methods do not accurately predict the risk of disease recurrence and benefit of adjuvant chemotherapy for patients who have had surgery for stage II colon cancer. We postulated that expression patterns of multiple microRNAs (miRNAs) could, if combined into a single model, improve postoperative risk stratification and prediction of chemotherapy benefit for these patients.<h4>Method</h4>Using miRNA microarrays, we analysed 40 paired stage II colon cancer tumours ...[more]

PMID: 24239208

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Dataset Information

The prognostic and predictive value of a six-microRNA-based classifier in stage II colon cancer

Publications

Prognostic and predictive value of a microRNA signature in stage II colon cancer: a microRNA expression analysis.

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