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Liver differentially expressed genes between microsomic and control inbred mice at birth

ABSTRACT: To understand the processes involved in the natural development of microsomic imbred mice, a whole genome microarray expression profiling of mouse liver was performed. Total RNA of liver from C57BL/6J microsomic mice of both sexes were extracted and compared with total RNA of liver from normal (control) mice of both sexes.

ORGANISM(S): Mus musculus

SUBMITTER: Alberto Miranda Bedate

PROVIDER: E-GEOD-49876 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Transcriptome profiling of liver of non-genetic low birth weight and long term health consequences.

Miranda Alberto A López-Cardona Angela P AP Laguna-Barraza Ricardo R Calle Alexandra A López-Vidriero Irene I Pintado Belén B Gutiérrez-Adán Alfonso A

BMC genomics 20140501

<h4>Background</h4>It is believed that the main factors of low prenatal growth in mammals are genetic and environmental. We used isogenic mice maintained in standard conditions to analyze how natural non-genetic microsomia (low birth weight) is produced in inbred mice and its long term effect on health. To better understand the molecular basis of non-genetic microsomia, we undertook transcriptome profiling of both male and female livers from small and normal size mice at birth.<h4>Results</h4>Na ...[more]

PMID: 24884990

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