Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Ann Rita Halvorsen
PROVIDER: E-GEOD-50220 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Halvorsen Ann Rita AR Helland Aslaug A Fleischer Thomas T Haug Karen Marie KM Grenaker Alnaes Grethe Irene GI Nebdal Daniel D Syljuåsen Randi G RG Touleimat Nizar N Busato Florence F Tost Jörg J Saetersdal Anna B AB Børresen-Dale Anne-Lise AL Kristensen Vessela V Edvardsen Hege H
International journal of cancer 20140405 9
Radiotherapy (RT) is a central treatment modality for breast cancer patients. The purpose of our study was to investigate the DNA methylation changes in tumors following RT, and to identify epigenetic markers predicting treatment outcome. Paired biopsies from patients with inoperable breast cancer were collected both before irradiation (n = 20) and after receiving 10-24 Gray (Gy) (n = 19). DNA methylation analysis was performed by using Illumina Infinium 27K arrays. Fourteen genes were selected ...[more]