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Expression data in KSHV-infected primary rat mesenchymal precursor (MM) cells

ABSTRACT: Kaposi's sarcoma-associated herpesvirus (KSHV) can efficiently infect and transform primary rat mesenchymal precursor (MM) cells. Regulation of cell cycle progression and apoptosis by KSHV-encoded microRNAs is required for KSHV-induced cellular transformation and tumorigenesis. To determine the roles of KSHV miRs in growth deregulation, we infected MM cells with the KSHV miR cluster deletion mutant and monitored infection by examining green fluorescence protein expression from a cassette inserted in the KSHV genome.

ORGANISM(S): Rattus norvegicus

SUBMITTER: Xiaodong Cui

PROVIDER: E-GEOD-50381 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Expression data in KSHV-infected primary rat mesenchymal precursor (MM) cells

Project description:Kaposi's sarcoma-associated herpesvirus (KSHV) can efficiently infect and transform primary rat mesenchymal precursor (MM) cells. Regulation of cell cycle progression and apoptosis by KSHV-encoded microRNAs is required for KSHV-induced cellular transformation and tumorigenesis.

2013-08-28 | GSE50381 | GEO

CD109 is novel KSHV entry receptor in human endothelial cells and enhances infection during cellular senescence

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2024-04-17 | PXD048212 | Pride

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