Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Laurent Corcos
PROVIDER: E-GEOD-50467 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Pesson Marine M Eymin Béatrice B De La Grange Pierre P Simon Brigitte B Corcos Laurent L
Molecular cancer 20140115
Alternative pre-mRNA splicing (AS) widely expands proteome diversity through the combinatorial assembly of exons. The analysis of AS on a large scale, by using splice-sensitive microarrays, is a highly efficient method to detect the majority of known and predicted alternative transcripts for a given gene. The response to targeted anticancer therapies cannot easily be anticipated without prior knowledge of the expression, by the tumor, of target proteins or genes. To analyze, in depth, transcript ...[more]