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Gamma-secretase inhibitor plus fludarabine in CLL

ABSTRACT: Combination of GSI with fludarabine has a synergistic antileukemic effect in primary NOTCH1-mutated CLL cells We used microarrays to detail the mechanism of synergy of GSI and fludarabine combination in NOTCH1-mutated CLL cells Global RNA expression in CLL primary cells treated with GSI, fludarabine and the combination at 48 hours of treatment

ORGANISM(S): Homo sapiens

SUBMITTER: DOLORS COLOMER

PROVIDER: E-GEOD-51044 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Gamma-secretase inhibitor plus fludarabine in CLL

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