Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Luc DesGroseillers
PROVIDER: E-GEOD-51182 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Boulay Karine K Ghram Mehdi M Viranaicken Wildriss W Trépanier Véronique V Mollet Stéphanie S Fréchina Céline C DesGroseillers Luc L
Nucleic acids research 20140606 12
Staufen1 (Stau1) is a ribonucleic acid (RNA)-binding protein involved in the post-transcriptional regulation of gene expression. Recent studies indicate that Stau1-bound messenger RNAs (mRNAs) mainly code for proteins involved in transcription and cell cycle control. Consistently, we report here that Stau1 abundance fluctuates through the cell cycle in HCT116 and U2OS cells: it is high from the S phase to the onset of mitosis and rapidly decreases as cells transit through mitosis. Stau1 down-reg ...[more]