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Gene expression in intestinal epithelial crypt and villus cell populations

ABSTRACT: We analyzed gene expression profiles in isolated mouse LGR5+ intestinal stem cells, lineage-specific enterocyte and secretory progenitors, and terminally differentiated villus enterocytes. Gene Ontology analyses of cell type-specific transcripts indicated their expected biological functions. We hybridized Affmetrix 430A 2.0 mouse microarrays with processed RNA isolated from purified Lgr5+ intestinal stem cells, secretory (Sec-Pro) and enterocyte (Ent-Pro) crypt progenitors, and mature villus enterocytes (ENT).

ORGANISM(S): Mus musculus

SUBMITTER: Fugen Li

PROVIDER: E-GEOD-51398 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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