Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Wenfei Jin
PROVIDER: E-GEOD-51505 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Kraushaar Daniel C DC Jin Wenfei W Maunakea Alika A Abraham Brian B Ha Misook M Zhao Keji K
Genome biology 20130101 10
<h4>Background</h4>Nucleosomes are present throughout the genome and must be dynamically regulated to accommodate binding of transcription factors and RNA polymerase machineries by various mechanisms. Despite the development of protocols and techniques that have enabled us to map nucleosome occupancy genome-wide, the dynamic properties of nucleosomes remain poorly understood, particularly in mammalian cells. The histone variant H3.3 is incorporated into chromatin independently of DNA replication ...[more]