Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

0

Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy


ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Homo sapiens

SUBMITTER: Enrique Carrillo de Santa Pau 

PROVIDER: E-GEOD-51641 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

altmetric image

Publications


Urothelial bladder cancer (UBC) is heterogeneous at the clinical, pathological and genetic levels. Tumor invasiveness (T) and grade (G) are the main factors associated with outcome and determine patient management. A discovery exome sequencing screen (n = 17), followed by a prevalence screen (n = 60), identified new genes mutated in this tumor coding for proteins involved in chromatin modification (MLL2, ASXL2 and BPTF), cell division (STAG2, SMC1A and SMC1B) and DNA repair (ATM, ERCC2 and FANCA  ...[more]

Similar Datasets

2013-10-24 | E-GEOD-51589 | biostudies-arrayexpress
2013-10-24 | E-GEOD-51640 | biostudies-arrayexpress
2015-06-19 | E-GEOD-64572 | biostudies-arrayexpress
2015-06-19 | E-GEOD-64573 | biostudies-arrayexpress
2010-04-11 | E-GEOD-21168 | biostudies-arrayexpress
2014-10-30 | E-GEOD-44974 | biostudies-arrayexpress
2014-07-01 | E-GEOD-30460 | biostudies-arrayexpress
2013-05-09 | E-GEOD-46733 | biostudies-arrayexpress
2013-06-05 | E-GEOD-47633 | biostudies-arrayexpress
2013-06-26 | E-GEOD-46828 | biostudies-arrayexpress