Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Emanuele Libertini
PROVIDER: E-GEOD-51867 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Frontiers in genetics 20151201
BAH domain-containing protein 1 (BAHD1) is involved in heterochromatin formation and gene repression in human cells. BAHD1 also localizes to the inactive X chromosome (Xi), but the functional significance of this targeting is unknown. So far, research on this protein has been hampered by its low endogenous abundance and its role in epigenetic regulation remains poorly explored. In this work, we used whole-genome bisulfite sequencing (BS-seq) to compare the DNA methylation profile of HEK293 cells ...[more]