Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Ryan Boudreau
PROVIDER: E-GEOD-52083 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Boudreau Ryan L RL Jiang Peng P Gilmore Brian L BL Spengler Ryan M RM Tirabassi Rebecca R Nelson Jay A JA Ross Christopher A CA Xing Yi Y Davidson Beverly L BL
Neuron 20140102 2
The orchestration of brain function requires complex gene regulatory networks that are modulated, in part, by microRNAs (miRNAs). These noncoding RNAs associate with argonaute (Ago) proteins in order to direct posttranscriptional gene suppression via base pairing with target transcripts. In order to better understand how miRNAs contribute to human-specialized brain processes and neurological phenotypes, identifying their targets is of paramount importance. Here, we address the latter by profilin ...[more]