Ontology highlight
ABSTRACT:
ORGANISM(S): Arabidopsis thaliana
SUBMITTER: Hongwei Guo
PROVIDER: E-GEOD-52409 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Zhang Xinyan X Zhu Ying Y Liu Xiaodan X Hong Xinyu X Xu Yang Y Zhu Ping P Shen Yang Y Wu Huihui H Ji Yusi Y Wen Xing X Zhang Chen C Zhao Qiong Q Wang Yichuan Y Lu Jian J Guo Hongwei H
Science (New York, N.Y.) 20150401 6230
Plant immunity against foreign gene invasion takes advantage of posttranscriptional gene silencing (PTGS). How plants elaborately avert inappropriate PTGS of endogenous coding genes remains unclear. We demonstrate in Arabidopsis that both 5'-3' and 3'-5' cytoplasmic RNA decay pathways act as repressors of transgene and endogenous PTGS. Disruption of bidirectional cytoplasmic RNA decay leads to pleiotropic developmental defects and drastic transcriptomic alterations, which are substantially rescu ...[more]