Long noncoding RNA expression in several hematopoietic progenitor and differentiated cell populations
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Ross Hardison
PROVIDER: E-GEOD-52555 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Lineage and species-specific long noncoding RNAs during erythro-megakaryocytic development.
Paralkar Vikram R VR Mishra Tejaswini T Luan Jing J Yao Yu Y Kossenkov Andrew V AV Anderson Stacie M SM Dunagin Margaret M Pimkin Maxim M Gore Meghneel M Sun Diana D Konuthula Neeraja N Raj Arjun A An Xiuli X Mohandas Narla N Bodine David M DM Hardison Ross C RC Weiss Mitchell J MJ
Blood 20140204 12
Mammals express thousands of long noncoding (lnc) RNAs, a few of which are known to function in tissue development. However, the entire repertoire of lncRNAs in most tissues and species is not defined. Indeed, most lncRNAs are not conserved, raising questions about function. We used RNA sequencing to identify 1109 polyadenylated lncRNAs expressed in erythroblasts, megakaryocytes, and megakaryocyte-erythroid precursors of mice, and 594 in erythroblasts of humans. More than half of these lncRNAs w ...[more]
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